Table 13.
Entry | Solvent | Yield % | ee% |
---|---|---|---|
1 | toluene | 90 | 88 |
2 | xylenes | 81 | 75 |
3 | benzene | 88 | 89 |
4 | Et2O | 67 | 87 |
5 | DMF | 71 | 73 |
6 | THF | 77 | 89 |
7 | CH2Cl2 | 16 | 67 |
8 | MeOH | 29 | −11 |
9 | EtOH | 63 | −42 |
10 | CF3CH2OH | 0 | NA |
11 | i-PrOH | 64 | −63 |
12 | i-BuOH | 30 | −57 |