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. Author manuscript; available in PMC: 2010 Jun 21.
Published in final edited form as: Synlett. 2009 May;8(2009):1189–1207. doi: 10.1055/s-0029-1216654

Table 4.

Effects of the Micheal acceptor on the intramolecular Stetter reaction. graphic file with name nihms-199310-t0049.jpg

Entry Substrate Product Yield % ee%
1 graphic file with name nihms-199310-t0050.jpg graphic file with name nihms-199310-t0051.jpg 94 95
2b graphic file with name nihms-199310-t0052.jpg graphic file with name nihms-199310-t0053.jpg 94 93
3b graphic file with name nihms-199310-t0054.jpg graphic file with name nihms-199310-t0055.jpg 94 97
4 graphic file with name nihms-199310-t0056.jpg graphic file with name nihms-199310-t0057.jpg 80 22
5b graphic file with name nihms-199310-t0058.jpg graphic file with name nihms-199310-t0059.jpg 94 92
6 graphic file with name nihms-199310-t0060.jpg graphic file with name nihms-199310-t0061.jpg 94 78
7 graphic file with name nihms-199310-t0062.jpg graphic file with name nihms-199310-t0063.jpg 85 70
8b graphic file with name nihms-199310-t0064.jpg graphic file with name nihms-199310-t0065.jpg 94 92
9 graphic file with name nihms-199310-t0066.jpg graphic file with name nihms-199310-t0067.jpg 88 80
10* 80 78
11b graphic file with name nihms-199310-t0068.jpg graphic file with name nihms-199310-t0069.jpg 50 30
*

20 mol % of catalsyt 33 was used.

b

Opposite antipode of the chiral triazolium salt 35 was used.