Table 2.
SPR results for KCNQ1 C-terminal domain binding to immobilized KCNE1 C-terminus and LQT5 mutants of KCNE1.
| Immobilized E1C | Kd | Rmax |
|---|---|---|
| WT | 4.5 ± 1.1 | 102 ± 11 |
| D76N | 3.1 ± 1.5 | 166 ± 32 |
| W87F | 4.1 ± 1.8 | 130 ± 25 |
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