Table 2.
IN transmission of CWD in Tg(cerPrP) mice
+, Present; − not present.
| Animal no. | Neurological signs* | Survival (days p.i.) | Weight loss (% max. body wt) | PrPCWD WB | PrPCWD IHC | TSE lesions |
|---|---|---|---|---|---|---|
| Sham n=9 | − | 361–755 | 5 (average) | − | − | − |
| 635 | + | 361 | 39 | − | − | − |
| 641 | + | 422 | 43 | + | + | + |
| 646 | + | 443 | 50 | − | − | − |
| 631 | + | 498 | 17 | + | + | + |
| 633 | − | 551 | +14 | − | − | − |
| 630 | − | 755 | 23 | − | − | − |
| 632 | − | 755 | 15 | − | − | − |
| 645 | − | 755 | 19 | − | − | − |
| 648 | − | 755 | 35 | − | − | − |
*Animals were considered positive if they exhibited at least three of the following symptoms: ataxia, lethargy, tremors, weight loss, poor coat quality or rigid tail.