Table 1.
Baseline characteristics of the RA patients per genotype of rs10818488
| GG n = 180 (29%) |
AG n = 324 (53%) |
AA n = 111 (18%) |
|
|---|---|---|---|
| Age (years) | 56.2 ± 15.2 | 56.3 ± 15.5 | 57.3 ± 16.5 |
| Females, n (%) | 132 (73.3) | 218 (67.3) | 71 (64.0) |
| Past or current smoker, n (%) | 83 (51.2) | 139 (48.1) | 53 (54.1) |
| Swollen joint count | 9.0 ± 6.6 | 9.4 ± 7.3 | 8.0 ± 6.0 |
| BMI (kg/m2) | 25.5 ± 3.7 | 25.7 ± 3.8 | 25.7 ± 4.0 |
| RF positive, n (%) | 101 (57.1) | 181 (57.3) | 70 (63.6) |
| Anti-CCP positive, n (%) | 75 (56.4) | 146 (57.5) | 46 (51.7) |
| CRP (mg/L) | 28.1 ± 29.0 | 31.6 ± 36.1 | 25.8 ± 30.1 |
| HAQ (0-3) | 1.05 ± 0.70 | 1.10 ± 0.72 | 1.03 ± 0.77 |
| Total Sharp- van der Heijde score, median (IQR 25-75) | 6 (2-13) | 6 (2-12) | 5 (1.5-11) |
Except if stated otherwise values are mean (standard deviation).
#Data not available for all cases (smoking status n = 66, swollen joint count n = 111, BMI n = 156, rheumatoid factor in n = 12, anti CCP n = 139, CRP n = 46, HAQ n = 113, Total Sharp- van der Heijde score n = 27).
BMI, body mass index; CCP, cyclic citrullinated peptide; CRP, C-reactive protein; IQR, interquartile range; HAQ, Health Assessment Questionnaire; RA, rheumatoid arthritis; RF, rheumatoid factor.