Table 3.
MASES, tender joint count, and swollen joint count by sex, HLA-B27 positivity, and concomitant DMARD use
All | Male | Female | HLA-B27-negative | HLA-B27-positive | No concomitant DMARD at baseline | Concomitant DMARD at baseline | |
---|---|---|---|---|---|---|---|
Median First quartile, third quartile [95% confidence interval] |
|||||||
Patients with enthesitis, MASES ≥ 1 at baseline | |||||||
MASES: 0 to 13, number (percentage) | 667 (100) |
431 (64.6) |
236 (35.4) |
126 (18.9)a |
523 (78.4)a |
499 (74.8) |
168 (25.2) |
Baseline | 5 2, 8 |
4 2, 7 |
7 4, 9 |
5 2, 9 |
5 2, 8 |
5 2, 8 |
4 2, 8 |
Week 12 | 1 0, 4 |
0 0, 2 |
1 0, 5 |
1 0, 5 |
0 0, 3 |
0 0, 3 |
1 0, 4 |
Change from baseline to week 12 | -2 -5,-1 [-3 to -2] |
-2 -5,-1 [-3 to -2] |
-3 -6,-1 [-4 to -2] |
-2 -5,-1 [-3 to -2] |
-3 -6,-1 [-3 to -2] |
-3 -5,-1 [-3 to -2] |
-2 -5,-1 [-5 to -2] |
Patients with peripheral arthritis, SJC ≥ 1 at baseline | |||||||
TJC: 0 to 46, number (percentage) | 281 (100) |
175 (62.2) |
106 (37.7) |
57 (20.3)a |
217 (77.2)a |
170 (60.5) |
111 (39.5) |
Baseline | 5 2, 12 |
4 2, 10 |
7 3, 14 |
6 3, 13 |
5 2, 12 |
4 2, 10 |
6 3, 13 |
Week 12 | 1 0, 3 |
1 0, 3 |
1 0, 4 |
1 0, 4 |
0 0, 3 |
0 0, 3 |
1 0, 4 |
Change from baseline to week 12 | -3 -8,-1 [-4 to -2] |
-2 -6,-1 [-3 to -2] |
-4 -10,-2 [-6 to -3] |
-3 -10,-1 [-6 to -2] |
-3 -7,-1 [-4 to -2] |
-2 -7,-1 [-3 to -2] |
-3 -9,-2 [-4 to -2] |
SJC: 0 to 44, number (percentage) | 281 (100) |
175 (62.2) |
106 (37.7) |
57 (20.3)a |
217 (77.2)a |
170 (60.5) |
111 (39.5) |
Baseline | 2 1, 4 |
2 1, 3 |
2 1, 6 |
2 1, 6 |
2 1, 4 |
2 1, 3 |
2 1, 6 |
Week 12 | 0 0, 1 |
0 0, 1 |
0 0, 1 |
0 0, 1 |
0 0, 1 |
0 0, 1 |
0 0, 1 |
Change from baseline to week 12 | -1 -3,-1 [-2 to -1] |
-1 -3,-1 [-2 to -1] |
-2 -4,-1 [-2 to -1] |
-1 -4,-1 [-2 to -1] |
-1 -3,-1 [-2 to -1] |
-1 -2,-1 [-1 to -1] |
-2 -4,-1 [-2 to -2] |
aBecause of missing data, the percentages of patients with HLA-B27 status do not sum to 100%. DMARD, disease-modifying antirheumatic drug; MASES, Maastricht Ankylosing Spondylitis Enthesitis Score; SJC, swollen joint count; TJC, tender joint count.