Table 1.
Baseline population characteristics
| Total (n = 116) | RA (n = 78) | UA (n = 38) | P | |
|---|---|---|---|---|
| Age | 52.5 [38.5-65.6] | 51.6 [43.0-66.7] | 53.5 [34.0-64.5] | NS |
| Female gender, n (%) | 90 (77.6) | 63 (80.7) | 27 (71.1) | NS |
| Disease duration (mo) | 6.1 [4.2-9.1] | 5.6 [4.0-8.4] | 6.75 [4.5-9.8] | NS |
| HAQ | 1.0 [0.5-1.5] | 1.1 [0.5-1.6] | 0.8 [0.5-1.3] | NS |
| DAS28 | 3.9 [3.2-5.2] | 4.5 [3.6-5.8] | 3.3 [2.8-4.6] | 0.001 |
| Rheumatoid factor, n (%) | 45 (38.8) | 38 (48.7) | 7 (18.4) | 0.002 |
| Anti-CCP, n (%) | 39 (33.6) | 36 (46.1) | 3 (7.9) | <0.001 |
| Comorbidities: n (%) | ||||
| Hypertension | 35 (30.2) | 22 (28.2) | 13 (34.2) | NS |
| Diabetes mellitus | 13 (11.2) | 8 (10.2) | 5 (13.2) | NS |
| Thyroid dysfunction | 17 (14.6) | 15 (19.2) | 2 (5.2) | 0.1 |
| Menopause (% of women) | 58 | 59 | 56 | NS |
| Age at menopause (years) | 50 [44-52] | 48 [44-50] | 52 [50-53] | 0.017 |
| Calcium intake (rare/moderate/high), (%) |
15/62/23 | 14/65/21 | 16/58/26 | NS |
| Smoking n (%) | 28 (24.1) | 19 (24.4) | 9 (23.7) | NS |
| Exercise (rare/moderate/intense) (%) | 38/47/15 | 42/42/16 | 29/58/13 | NS |
| Body mass index (kg/m2) | 26.5 [24.5-30.5] | 26.0 [24.0-30.0] | 28.0 [26.0-30.9] | NS |
| Prior personal fractures (%) | 17 | 18 | 16 | NS |
| Prior family fractures (%) | 19 | 18 | 24 | NS |
Data are shown as the percentage of patients or as the median and interquartile range.
Abbreviations: anti-CCP, antibodies directed to cyclic citrullinated peptide; DAS28, disease activity score in 28 joints; HAQ, health assessment questionnaire; NS, not statistically significant; RA, rheumatoid arthritis; UA, undifferentiated arthritis.