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. 2010 Mar 30;12(2):R56. doi: 10.1186/ar2968

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Copyright ©2010 Sun et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Comparison of osteoarthritis meniscal cell-mediated and osteoarthritis chondrocyte-mediated calcium deposition. (a) ATP-induced calcium deposition in the monolayer cultures of osteoarthritis (OA) meniscal cells derived from four OA patients (OA-M) (see Table 3) was 60% greater than present in the monolayer cultures of OA hyaline articular chondrocytes (OA-C). The difference was statistically significant (*P < 0.05). (b) Calcium phosphocitrate (CaPC) inhibited ATP-induced calcium deposition in the monolayer cultures of OA meniscal cells in a dose-dependent manner (*P < 0.001). Count per minute (CPM) data were normalized against total protein levels.