Table 1.
Course of disease: clinically and radiologically identified lesions located in all body regions
| Location | 0 months | 3 months | 6 months | 12 months | Total in first year |
|---|---|---|---|---|---|
| Clinical lesions | 2.1 | 0.8 | 0.6 | 0.5 | 1.0 |
| Mean | |||||
| Absolute number | 79 | 27a | 21a | 19a | 184 |
| Head | 1 (1.3) | 1 (3.7) | 1 (4.8) | 1 (5.3) | 4 (2.7) |
| Extremities | 38 (48.1) | 15a (55.6) | 14a (66.7) | 10a (52.6) | 77 (53.3) |
| Thorax | 15 (19.0) | 6a (22.2) | 2a (9.5) | 4a (21.1) | 27 (19.6) |
| Spine | 7 (8.9) | 1a (3.7) | 2a (9.5) | 1a (5.3) | 11 (6.5) |
| Pelvis | 18 (22.8) | 4a (14.8) | 2a (9.5) | 3a (15.8) | 27 (17.9) |
| Radiological lesions | |||||
| Mean | 5.0 | 3.7 | 2.5 | 2.2 | 3.4 |
| Absolute number | 184 | 121 | 89a | 81a | 475 |
| Head | 1 (0.5) | 1 (0.8) | 1 (1.1) | 1 (1.2) | 4 (0.8) |
| Extremities | 91 (49.5) | 78 (64.5) | 66 (74.1) | 63 (77.7) | 298 (62.7) |
| Thorax | 19 (10.3) | 11 (9.1) | 10 (11.2) | 6a (7.4) | 46 (9.7) |
| Spine | 27 (14.7) | 9 (7.4) | 2a (2.2) | 2a (2.5) | 40 (8.4) |
| Pelvis | 46 (25.0) | 22 (18.2) | 10a (11.2) | 9a (11.1) | 87 (18.3) |
Results presented as absolute numbers (%). Statistical analysis performed using analysis of variance. Head involvement was noted in one patient, where the os zygomaticum was affected.aP < 0.05 versus month 0.