Table 2.
Factor | Pretreatment | Sham | CHF |
---|---|---|---|
n | 51 | 24 (4 wk) | 27 (4 wk) |
BW, kg | 2.85 ± 0.12 | 3.66 ± 0.10 | 4.08 ± 0.12 |
LVW/BW, g/kg | 1.62 ± 0.06 | 2.16 ± 0.07* | |
LVEDD, mm | 13.10 ± 0.50 | 13.90 ± 0.40 | 16.80 ± 0.40* |
LVESD, mm | 8.20 ± 0.30 | 8.40 ± 0.30 | 12.70 ± 0.30* |
FS, % | 39.70 ± 1.70 | 40.40 ± 1.20 | 21.10 ± 1.60* |
EF, % | 75.80 ± 1.50 | 75.20 ± 1.40 | 48.10 ± 1.90* |
Values are means ± SE, where n represents number of animals. CHF, chronic heart failure; LVW/BW, ratio of left ventricular weight to body weight; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; FS, fractional shortening; EF, ejection fraction.
P < 0.05 versus Sham.