Fig. 2.

The onset of the dual-component EPSCs was stable at high-frequency DR stimulation and in the presence of mephenesin. Superimposed are 3 successive EPSCs in the order of black, red, and green traces. A₁: dual-component EPSCs with latencies of 6 and 12 ms were generated by L2 DR stimuli at 0.1 Hz. A₂: the onset of EPSCs did not change at higher-frequency stimulation (5 Hz). In this and all other panels, arrows point to the first evoked EPSCs. B₁: DR-evoked EPSCs in L3 Hb9 IN. B₂: exposure to mephenesin (1 mM) did not alter the onset of the dual-component EPSCs, but blocked all EPSCs with latencies >20 ms. C₁: L1 DR stimuli at 0.1 Hz generated EPSC with latencies of 14.7 ± 1.2 ms. C₂: EPSC onset became more consistent in the presence of mephenesin that blocked EPSCs with latencies >20 ms. D₁: extensor-related, L5 DR stimulation evoked longer-latency EPSCs (33.5 ms) in L1 Hb9 IN. D₂: L5 DR-evoked EPSCs were suppressed during exposure to mephenesin.