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. 2010 Apr 21;103(6):3448–3464. doi: 10.1152/jn.01069.2009

Fig. 2.

Fig. 2.

NMDAR currents are strongly inhibited by [Mg]o within the mouse SCN. The NMDAR I-Vs are plotted as an average (±SE) where each cell was scaled to its outward current at 50 mV, for all [Mg]o conditions in experiments conducted during the subjective night (SN; A, black, n = 9) and subjective day (SD; B, gray, n = 15). In the 0 μM [Mg]o condition, no [Mg]o was added to extracellular solutions. C: outward NMDAR currents at 50 mV are plotted as a function of [Mg]o for the SN (black circle) and SD (gray square). D: inward NMDAR currents at −25 mV (empty) and −65 mV (filled) are plotted as a function of [Mg]o for the SN (black circle, n = 9) and SD (gray square, n = 15). E: the IC50 (natural log) of [Mg]o (in μM) is plotted as a function of voltage (mV) for the SN (black circle, n = 9) and SD (gray square, n = 15). The scale is set to A and B is 20 mV (horizontal bar) and 0.5 arbitrary units (vertical bar).