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Summary of the 30 hMC4R polymorphisms examined in this study. The dashed line indicates the N-terminal FLAG sequence used for immunohistochemical cell expression studies. Changes in key receptor pharmacological profiles are indicated by either a change in font color and/or a colored callout circle, as indicated in the figure. The lavender color indicates hMC4R residues postulated to be involved in the putative ligand binding pocket.
