. 2010 Apr 23;285(26):19738–19746. doi: 10.1074/jbc.M110.101287

TABLE 1.

Amino acid alignment of swapped region in TMD-swap PS1 mutants

Alignments of amino acid sequences of the TMDs of PS1 and CD4 or CLAC-P are shown. Numbers indicate the region for TMD-swap mutant in PS1. Amino acid sequences remained as those of PS1 in TM6mt are underlined.

TM1mt	`⁸²VIMLFVPVTLCMVVVVATI¹⁰⁰`	PS1 TMD1
	`⁸²CAVLAALLSVVAVVSCLYL¹⁰⁰`	CLAC-P
TM2mt	`¹³⁵NAAIMISVIVVMTILLVVLY¹⁵⁴`	PS1 TMD2
	`¹³⁵ALIVLGGVAGLLLFIGLGIF¹⁵⁴`	CD4
TM3mt	`¹⁶⁴AWLIISSLLLLFFFSFIYLG¹⁸³`	PS1 TMD3
	`¹⁶⁴CAVLAALLSVVAVVSCLYLG¹⁸³`	CLAC-P
TM4mt	`¹⁹⁰NVAVDYITVALLIWNFGVVGMISI²¹³`	PSI TMD4
	`¹⁹⁰MALIVLGGVAGLLLFIGLGIFFCV²¹³`	CD4
TM5mt	`²¹⁹LRLQQAYLIMISALMALVFI²³⁸`	PS1 TMD5
	`²¹⁹CAVLAALLSVVAVVSCLYLG²³⁸`	CLAC-P
TM6mt	`²⁴⁴WTAWLILAVISVYDLVAVL²⁵⁵`	PS1 TMD6
	`²⁴⁴MALIVLGGVAGLYDLVAVL²⁵⁵`	CD4/TMD6
TM8mt	`⁴⁰⁸IACFVAILIGLCLTLLLLAIF⁴²⁸`	PS1 TMD8
	`⁴⁰⁸MALIVLGGVAGLLLFIGLGIF⁴²⁸`	CD4
TM9mt	`⁴³⁴ALPISITFGLVFYFATDYLV⁴⁵³`	PS1 TMD9
	`⁴³⁴CAVLAALLSVVAVVSCLYLG⁴⁵³`	CLAC-P