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. 2010 Apr 19;285(26):20242–20251. doi: 10.1074/jbc.M109.087031

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© 2010 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 7. — Fibrillin-2 microfibrils are unmasked in mouse Fbn1 null tissues. P8 wild type (A, C, E, and G) and Fbn1^−/− (B, D, F, and H) littermate sections were stained with pAb 0868, specific for fibrillin-2. Fibrillin-2 immunostaining was mostly negative in wild type sections of skin (A) and skeletal muscle (C) at this time; there was weak fibrillin-2 immunostaining in wild type sections of tendon (E) and perichondrium (F). However, in Fbn1^−/− sections, fibrillin-2 immunostaining was revealed in typical tissue-specific fibrillin microfibril patterns (B, D, F, and H). Scale bar, 50 μm.