Table 3.
Brain Regions With Significant Activation Within Healthy Control and Schizophrenic Patient Groups by Task
Brain Regiona | Volume, mm3 | Brodmann Area |
Talairach Coordinates, x, y, z |
---|---|---|---|
N-Back in Controls | |||
Right superior frontal gyrus | 1600 | 6 | 2, 8, 48 |
Left middle frontal gyrus | 4888 | 6 | −42, 2, 40 |
720 | 10 | −36, 40, 24 | |
408 | 6 | −22, −12, 52 | |
Right middle frontal gyrus | 1104 | 10 | 36, 44, 16 |
Right inferior frontal gyrus | 2072 | 9 | 46, 14, 22 |
Right precentral gyrus | 1072 | 6 | 32, −8, 54 |
Right anterior cingulate gyrus | 952 | 32 | 2, 24, 38 |
Left inferior parietal lobule | 3384 | 40 | −38, −54, 38 |
Right precuneus | 2360 | 19 | 32, −62, 38 |
Left cerebellum declive | 3024 | −36, −68, −14 | |
Left cerebellum, cerebellar tonsil | 608 | −36, −54, −38 | |
Right cerebellum declive | 1048 | 30, −64, −16 | |
Right cerebellum anterior lobe | 832 | 32, −56, −28 | |
568 | 0, −54, −28 | ||
Left claustrum | 2240 | −30, 20, 2 | |
Left thalamus ventral anterior nucleus | 1760 | −12, −8, 12 | |
Right thalamus | 816 | 4, −22, 8 | |
| |||
N-Back in Schizophrenic Patients | |||
Left middle frontal gyrus | 1616 | 6 | −32, −2, 48 |
1568 | 9 | −42, 14, 28 | |
Right middle frontal gyrus | 3272 | 9 | 46, 8, 34 |
Right anterior cingulate gyrus | 1648 | 32 | 6, 18, 42 |
Right superior parietal lobule | 1952 | 7 | 24, −64, 42 |
Left inferior parietal lobule | 1240 | 40 | −38, −48, −40 |
Right inferior parietal lobule | 736 | 40 | 40, −46, 40 |
Left cerebellum declive | 944 | −36, −62, −16 | |
672 | −6, −72, −14 | ||
Right cerebellum culmen | 1304 | 38, −52, −18 | |
Left insula | 664 | 13 | −36, 14, −2 |
| |||
Delayed Match to Sample in Controls | |||
Right middle frontal gyrus | 840 | 11 | 28, 44, −10 |
Left inferior frontal gyrus | 592 | 45 | −40, 20, 4 |
| |||
Delayed Match to Sample in Schizophrenic Patients | |||
Left middle frontal gyrus | 728 | 46 | −50, 28, 20 |
Right middle frontal gyrus | 1000 | 9 | 36, 30, 28 |
Left inferior frontal gyrus | 856 | 9 | −58, 6, 22 |
Left superior parietal lobule | 520 | 7 | −36, −70, 46 |
Right insula | 688 | 30, 22, 2 | |
| |||
Go/No-Go in Controls | |||
Left superior frontal gyrus | 576 | 9 | −28, 50, 34 |
Left middle frontal gyrus | 648 | 9 | −40, 14, 28 |
Right middle frontal gyrus | 640 | 9 | 42, 22, 28 |
640 | 6 | 42, 6, 48 | |
Right inferior frontal gyrus | 448 | 13 | 36, 22, 6 |
Right precentral gyrus | 552 | 9 | 40, 8, 36 |
Left postcentral gyrus | 464 | 3 | −42, −22, 40 |
Right postcentral gyrus | 512 | 2 | 52, −22, 34 |
Left claustrum | 544 | −30, 14, 0 | |
Right thalamus | 736 | 14, −14, 2 | |
| |||
Go/No-Go in Schizophrenic Patients | |||
Left middle frontal gyrus | 1776 | 9 | −36, 12, 26 |
Right middle frontal gyrus | 664 | 10 | 38, 36, 24 |
Right inferior frontal gyrus | 792 | 9 | 40, 8, 30 |
Right anterior cingulate gyrus | 712 | 32 | 2, 14, 38 |
Right inferior parietal lobule | 752 | 40 | 42, −32, 38 |
| |||
Stroop in Controls | |||
Left precentral gyrus | 728 | 6 | −42, 0, 34 |
Right anterior cingulate gyrus | 464 | 32 | 2, 14, 40 |
Left middle temporal gyrus | 1072 | 21 | −58, −48, 6 |
Right supramarginal gyrus | 680 | 40 | 54, −50, 24 |
Left precuneus | 560 | 7 | −24, −64, 30 |
416 | 7 | −14, −66, 44 | |
Right precuneus | 680 | 31 | 26, −72, 18 |
Left claustrum | 688 | −28, 18, 4 | |
| |||
Stroop in Schizophrenic Patients | |||
Right middle frontal gyrus | 1840 | 46 | 40, 28, 14 |
Right precentral gyrus | 696 | 6 | 36, 2, 36 |
Left postcentral gyrus | 528 | 5 | −20, −42, 66 |
Right cuneus | 1048 | 18 | 24, −76, 18 |
Right insula | 464 | 13 | 32, 16, −6 |
Left thalamus | 672 | −12, −12, 2 |
Regions are listed in hierarchical order based on the following nested criteria: cortical to cerebellar to subcortical, rostral to caudal, dorsal to ventral, left to right, and large to small.