. Author manuscript; available in PMC: 2010 Jun 21.

Published in final edited form as: Lab Invest. 2008 Dec 29;89(2):209–221. doi: 10.1038/labinvest.2008.127

Table 1. Effect of PTK/ZK on serum markers in experimental liver fibrosis.

	Hyaluronic acid (ng/ml)	TBil (μmol/l)	AST (U/l)	ALT (U/l)	ALB (g/l)
Control	12.5±5.1	1.1±0.5	36.5±4.6	15.5±2.7	31.1±0.8
CCl₄ 6 weeks	391.0±12.7	3.3±0.6	949.3±65.9	421.8±66.9	33.8±2.4
(CCl₄+PTK/ZK) 6 weeks	93.1±6.6^*	1.7±0.4	47.7±6.1^*	24.0±3.5^*	33.5±0.6
CCl₄ 2 weeks	253.4±17.5	2.6±0.3	642.3±84.5	274.8±33.7	37.4±1.2
CCl₄ 8 weeks	479.8±29.7	5.5±0.4	1068.2±96.3	501.1±53.6	36.0±0.9
CCl₄ 2 weeks+(CCl₄+PTK/ZK) 6 weeks	177.2±23.4^*	3.4±0.4	177.1±26.4^*	58.6±15.4^*	34.0±1.1
CCl₄ 4 weeks	338.7±26.3	4.7±0.5	865.4±124.5	340.9±23.7	34.8±1.7
CCl₄ 10 weeks	518.1±47.6	5.1±0.7	968.2±64.3	469.7±36.5	35.6±2.8
CCl₄ 4 weeks+(CCl₄+PTK/ZK) 10 weeks	237.5±33.4^*	2.8±0.3	231.7±39.4^*	115.3±24.3^*	34.1±2.2

TBil: total bilirubin; AST: aspartate aminotransferase; ALT: alanine aminotransferase; ALB: albumin.

Data are mean±s.e., n = 8.

P<0.01.