Table 5.

Adverse Effects of Various Therapies

Topical antifungal agents (e.g., azoles, allylamines): irritant contact dermatitis, itching, burning, dryness

Metronidazole: contact sensitization

Selenium: hyperpigmentation (rare)

Tea tree oil: irritant contact dermatitis

Topical corticosteroids: skin atrophy, telangiectasis, folliculitis, hypopigmentation

Immunomodulators: questionable association with lymphoma

Tar: hyperpigmentation, exfoliative dermatitis, skin atrophy, keratoacanthomas, malignancy

Phototherapy: burning, itching, increased risk of malignancy with long-term use