Table 3.
Serum measurements
| HFD (n = 10) | SBD (n = 11) | HFD/SBD | P Value | |
|---|---|---|---|---|
| Leptin, ng/ml | 17.03 ± 5.70 | 2.37 ± 0.87 | 7.18 | <0.001 |
| Insulin, ng/ml | 8.57 ± 5.16 | 1.73 ± 0.76 | 4.95 | <0.001 |
| Glucose, mg/dl | 160.9 ± 16.29 | 118.9 ± 8.84 | 1.35 | <0.001 |
| Triglycerides, mg/dl | 112.9 ± 27.05 | 139.6 ± 13.72 | 0.81 | 0.009 |
| NEFA, meq/l | 1.82 ± 0.25 | 2.03 ± 0.19 | 0.90 | 0.044 |
| Total cholesterol, mg/dl | 120.8 ± 9.29 | 73.45 ± 5.85 | 1.65 | <0.001 |
| HDL cholesterol, mg/dl | 116.5 ± 10.95 | 52.48 ± 4.90 | 2.22 | <0.001 |
| non-HDL cholesterol, mg/dl | 3.59 ± 4.78 | 19.23 ± 6.74 | 0.19 | <0.001 |
| T4 thyroid hormone, μg/dl | 4.95 ± 0.68 | 7.23 ± 1.19 | 0.69 | <0.001 |
Serum values are means ± SD for n mice. Measurements were done on 12-wk-old males after feeding of either HFD or SBD between 6 and 12 wk of age. Serum was collected 2 h after fasting at 1:00 PM. NEFA, nonesterified fatty acids; HDL, high-density lipoprotein.