Table 1. The top five biological networks in bovine GV oocyte proteome.
| Network IDs | Proteins in Networka) | Scoreb) | Focus Proteins | Top Functions |
| 1 | Akt, ANGPTL3, C17ORF61, C7ORF20, DDB1, EEF2, EEF1A1, EEF1A2, EEF1B2, EEF1D, EEF1G, ENO1, ENO3, Enolase, FAM62A, GPI, HARS, HRNR, HYOU1, ILF2 (includes EG:3608), KRT10, PDCD5, PHIP, PLA2G1B, PPT1, Protein-synthesizing GTPase, RAD23B, RAI14, RPS7, SRGAP1, TSFM (includes EG:10102), TUBB4, TUFM, WARS, YWHAZ | 52 | 32 | Protein synthesis, Lipid metabolism, Small- molecule biochemistry |
| 2 | AHCY, AK2, AURKA, CACYBP, DDX6, EIF4ENIF1, EIF5A, ELAVL1, G3BP1, H2AFX, HIST3H2A, HMGB2, HNRNPK, Importin alpha/beta, Importin beta, NME2, NUP50, PCBP2, PCBP1 (includes EG:5093), PDIA6, Pkc(s), RAG1, RALY, RAN, RBMX, RPL23, RPS2, RPS20, TAGLN, TERF1, TGM1, TLN1, UBE2N, UGP2, UQCRC2 | 52 | 32 | Molecular transport, Protein trafficking, Amino acid metabolism |
| 3 | ACR, Adenosine-tetraphosphatase, ALDH2, ATP synthase, ATP5A1, ATP5B, ATP5C1, ATP5G2, ATP5O, ATPase, BAT1, ERK, ETFA (includes EG:2108), ETFB (includes EG:2109), FAU, FHIT, GOT, GOT2, H+-transporting two-sector ATPase, HSPD1, HSPE1, M6PRBP1, MAPKAPK3, MFGE8, MVP, NSF, PJA1, RAB1A, RAB2A, RAB7A, RABEP1, Rsk, STX12, ZP2, ZP3 | 42 | 28 | Cell-to-cell signaling and interaction, Reproductive system development and function, DNA replication, recombination, and repair |
| 4 | 26s Proteasome, AGA, COX5B, DNAJA1, DNMT1, EPHA2, FKBP4, HSP, Hsp70, Hsp90, HSP90AA1, HSP90AB1, HSPA2, HSPA5, HSPA6, HSPA8, HSPA9, HSPB1, HSPH1, IARS2, MDH1, MTHFD1, Nos, PARK7, PARP1, PFN1, PGK1, PI3K, PPA1, PSAP, PTGES3 (includes EG:10728), RPL7, RPS3A, Shc, STIP1 | 42 | 28 | Cellular function and maintenance, Cellular compromise |
| 5 | AICDA, Ant, CYCS (includes EG:54205), Cytochrome c oxidase, DDOST, Dolichyl-diphosphooligosaccharide-protein glycotransferase, Glutathione peroxidase, GPX1, IL1F5, INPP1, Ldh, LDHA, LDHB, NF-kappaB (family), NFkB (complex), PECAM1, peroxidase (miscellaneous), PRDX1, PRDX2, PRDX3, PRDX4, PRDX5, PRDX6, RAB3C, RPN1, RPN2, SLC25A3, SLC25A4, SLC25A10, SLC25A13, Sod, SOD2, TRPM8, TXN, VDAC1 | 38 | 26 | Small molecule biochemistry, Molecular transport, Cellular function and maintenance |
a) The focus proteins are indicated with gene names and shown in bold letters.
b) A score of >2 is considered statistically significant.