Figure 6. Low-dose IR enhances angiogenesis in Matrigel plug assay.
Angiogenesis was induced by injection of growth factor-depleted Matrigel with FGF2. (A) Macroscopic evaluation of the Matrigel plugs explanted 5 d after injection in non-irradiated and 0.3 Gy preirradiated area. Scale bars, 500 µm. (B) Angiogenesis was quantified by determining the angiogenic index. Inset shows the mean difference of angiogenic index between paired mice. * P<0.025.