Figure 2. Capture of the chromosome 9 QTL for the locomotor response to ethanol is dependent on congenic background strain.
(a) The acute locomotor response to ethanol (2 g/kg) in male and female chromosome 9 D2.B6 (D9Mit90,18; 9–71 cM) congenic, chromosome 9 B6.D2 – short (D9Mit90,182; 9–58 cM) congenic, D2 and B6 strains. (b) The acute locomotor response to ethanol (1.5 g/kg) in male and female chromosome 9 B6.D2 – short (D9Mit90,182; 9–58 cM) congenic and B6 strains. (c) The acute locomotor response to ethanol (2 g/kg) in male and female chromosome 9 B6.D2 – long (D9Mit90,18; 9–71 cM) congenic and B6 strains. Data are for the first 5 min (mean ± SEM) of the 15-min test session. *P < 0.05.
