Figure 3. QTL mapping in a congenic F2 population reduces the QTL interval from a 62 cM region to a 46 cM region.
The peak LOD score for the chromosome 9 QTL is at 59 cM with a 1 LOD support interval of 23–69 cM. Shown are LOD scores representing the most likely location of the QTL for ethanol (2 g/kg)-induced stimulation on chromosome 9 based on interval mapping in the chromosome 9 D2.B6 (D9Mit90,18; 9–71 cM) congenic × D2 F2 mice. n used for mapping = 32 mice from the bottom and top tails of the phenotypic distribution curve.
