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. 2010 Jun 21;5(6):e11239. doi: 10.1371/journal.pone.0011239

Figure 2. Effect of Genz-112638 on A) food consumption and B) body weight.

Figure 2

C57BL/6 mice were fed a normal diet (Lean) or a HFD (DIO) for 8 weeks. The DIO or Lean mice were then treated with Genz-112638 or placebo (water) by daily oral gavage (125 mg/kg/day) for 12 weeks, while remaining on their respective diets. Data shown as mean ± SEM (n = 7–14 mice per group). *P<0.05 Genz-112638 DIO (both doses) vs. Water DIO, weeks 0–9. There was no significant difference in body weights between the Water DIO and drug treated groups.