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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Langmuir. 2009 Mar 3;25(5):2860–2864. doi: 10.1021/la803523b

Scheme 1.

Scheme 1

Synthesis of bifunctionalized PEG linker 6 and succinimidyl active esters 8 and 10. Reagents and conditions: (a) TsCl, Py, 0 °C; (b) KSAc, CH3OH, reflux; (c) TsCl, Py, 0 °C; (d) NaN3, DMF, 60 °C; (e) NaOCH3, CH3OH, rt. a) EDC, NHS, DCM, rt; (b) DCC, NHS, dioxane, rt;