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The reverse sulfonamide analogs of 5824 and their biological activities.
| ID | NADs IC50 (µM) | LB B.a. MIC (µM[µg/mL]) | MH B.a. MIC (µM[µg/mL]) |
|---|---|---|---|
| 5824 | 6.4 | 1.9 [0.9] | 2.8 [1.3] |
| 5{1} | 32.7 | 2.8 [1.3] | 3.8 [1.8] |
| 5{2} | 95.5 | > 240 [>115] | – a |
| 5{3} | 443 | > 240 [>115] | – a |
Compounds which showed no inhibition in the LB MIC assay were not included in the MH assay.
