Skip to main content
. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Anesth Analg. 2010 Aug;111(2):444–450. doi: 10.1213/ane.0b013e3181aa8903

Table 1.

Impact of practice misalignments in the trial of treatments for opioid dependence

Control group Withdrawn from study Adverse event rate
Low-dose methadone 44/55 0/55
Treatment groups Withdrawn from study
(p-value)		 Adverse event rate
(p-value)
High-dose methadone 15/55
(<0.0001)		 3/55
(0.08)
Buprenorphine 23/55
(<0.0001)		 2/55
(0.15)
Levomethadyl acetate 26/55
(0.0007)		 8/55
(0.003)

P-values are from chi-square tests comparing the rates between the control group and the individual treatment group listed.