Table 3.
Mean±SEM change in laboratory values by sex and bicarbonate treatment statusa
Number | Men |
Women |
||||
---|---|---|---|---|---|---|
Control | Bicarbonate | P | Control | Bicarbonate | P | |
35 | 36 | 49 | 42 | |||
24-h urine | ||||||
Creatinine (Cr; mmol) | 0.67±0.54 | −0.27±0.53 | 0.225 | 0.55±0.24 | 0.71±0.26 | 0.671 |
Nitrogen/Cr (mmol/mmol) | −1.53±2.50 | −2.58±2.50 | 0.767 | 2.50±2.02 | −6.14±2.18 | 0.004 |
NAE/Cr (mmol/mmol) | −0.23±0.25 | −2.87±0.25 | <0.001 | 0.47±0.29 | −4.11±0.31 | <0.001 |
Potassium/Cr (mmol/mmol) | 1.41±0.51 | 1.49±0.50 | 0.916 | 1.43±0.51 | 1.92±0.55 | 0.519 |
Sodium/Cr (mmol/mmol) | 1.26±0.67 | 2.57±0.66 | 0.171 | 0.36±0.66 | 1.27±0.71 | 0.348 |
Serum | ||||||
PTH (pmol/L) | −0.01±0.27 | −0.36±0.27 | 0.377 | −0.25±0.20 | 0.19±0.21 | 0.139 |
IGF-1 (nmol/L) | 17.59 ±18.43 | 21.57±18.21 | 0.880 | 7.50±20.04b | 9.10±21.49 | 0.959 |
Changes are adjusted for baseline laboratory value and changes in urinary sodium/Cr and urinary potassium/Cr.
N=48