Fig. 2.

Morphology and distribution of CD16+ cells in oral mucosal samples. Sections of archival specimens were stained by immunohistochemistry for CD1a or for CD16. CD1a+ cells (left) and CD16+ cells (right) have brown cell-surface labeling, and the nuclei are counterstained blue. a Oral squamous cell carcinoma (OSCC) samples contain CD16+ cells with dendritic morphology that are similar in morphology and distribution to CD1a+ DC. b Similar to SCC, CD16+ round cells and cells with dendritic morphology are present in inflamed mucosa in the absence of pre-malignant/malignant epithelial change.