Table 5.
Inhibitory activity of ML-OVA on the association between sCD4 and distinct HIV envelope proteins.
| Chemically modified protein | Inhibitory activity (μM)a | The HIV envelope proteins | |||
|---|---|---|---|---|---|
| gp120 of HIV-1IIIB | gp120 of HIV-1MN | gp120 of HIV-1BaL | gp105 of HIV-2ROD | ||
| ML-OVA | IC50 | 0.471 ± 0.063 | 1.161 ± 0.092 | 1.397 ± 0.008 | 0.466 ± 0.076 |
| IC90 | 3.258 ± 0.413 | 8.567 ± 2.360 | 19.77 ± 1.491 | 11.36 ± 3.721 | |
| OVA | IC50 | >100 | >100 | >100 | >100 |
| IC90 | >100 | >100 | >100 | >100 | |
aThe measurements were performed in triplicate, and the experiment was repeated twice. Data are presented in means ± SD.