Table 2.

Allele frequencies and P-value for test of significance of departure from Hardy-Weinberg equilibrium expectations for 12 INSIG2 tagSNPs in each racial group.

					Blacks (N=2, 129)		Whites (N=2,175)
Polymorphism	Chromosomal position	Gene Location	Allele 1	Allele 2	Freq (allele 1)	HWE P	Freq (allele 1)	HWE P
rs7566605	118552495	5′ flanking	C	G	0.26	0.15	0.33	0.32
rs10185316	118560948	5′ flanking	G	C	0.30	0.40	0.32	0.66
rs4848492	118561741	5′ flanking	C	T	0.20	0.59	0.10	0.61
rs13428113	118563355	Intron 1	C	T	0.41	0.24	0.58	0.65
rs1352083	118564311	Intron 1	T	C	0.27	0.70	0.25	0.82
rs12464355	118566320	Intron 1	G	A	0.01	1.00	0.09	0.11
rs17528324	118572626	Intron 2	A	G	0.01	1.00	0.05	0.67
rs889904	118576941	Intron 2	G	A	0.40	0.96	0.52	0.28
rs10490624	118578962	Intron 3	G	A	0.11	0.14	0.09	0.59
rs13409050	118580240	Intron 3	A	G	0.25	0.48	0.07	0.63
rs9308762	118580344	Intron 3	C	T	0.14	0.06	0.17	0.75
rs17047764	118585051	3′ flanking	C	G	0.39	0.37	0.16	0.81