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HPLC retention time and log P values for 99mTc-labeled cyclic RGD peptides.
| Compound | RCP (%) | RT (min) | Log P |
|---|---|---|---|
| 99mTcO(MAG2-P-RGD2) | > 95 | 17.0 | - 3.30 ± 0.13 |
| 99mTcO(MAG2-3P-RGD2) | > 90 | 16.9 | -3.19 ± 0.15 |
| 99mTcO(MAG2-3P-RGK2) | > 90 | 17.3 | -2.40 ± 0.14 |
| 99mTc-3P-RGD2 | > 90 | 16.9 | -4.35 ± 0.10* |
The log P value of −3.96 ± 0.05 was reported in our previous communication (55). These two values seem to be statistically significant; but they are within the experimental error of the assay.
