Examination of dendrimer-lipid complexes, as measured by AFM, TEM, and ITC, and estimated from models. Results are compared by both volume and stoichiometry by assuming a constant density of lipids (1.5 nm3/lipid) and one dendrimer per complex. ITC, TEM, and AFM results suggest the average G8-DMPG complex is consistent with the dendrimer-encased vesicle model (Fig. 5B). The volume of dendrimers in the absence of lipids was previously measured.38, 43