Table 3.
Age-adjusted risk factors by sex and diabetes status
| Women | Men | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| NGT (n=176) |
Impaired fasting glucose n=(83) |
Diabetic (n= 89) |
NGT (n=420) |
Impaired fasting glucose (n=307) |
Diabetic (n=151) |
|||||||||
| Mean | (SD) | Mean | (SD) | Mean | (SD) | p | Mean | (SD) | Mean | (SD) | Mean | (SD) | p | |
| Age (years) | 56.3 | (8.6) | 56.6 | (8.6) | 56.6 | (8.2) | .920 | 53.4 | (9.0) | 55.0 | (8.5) | 56.8 | (7.6) | <.001 |
| Fasting total cholesterol (mg/dl) | 196.8 | (44.2) | 194.0 | (40.6) | 202.1 | (39. | .462 | 177.9 | (40. | 185.3 | (40.6) | 180.4 | (51.5) | .068 |
| Serum creatinine (mg/l) | .9 | (.8) | .8 | (.2) | 1.0 | (0.7) | .277 | 1.0 | (.6) | 1.1 | (1.2) | 1.0 | (0.3) | .293 |
| Fasting glucose (mg/dl) | 90.0 | (6.7) | 108.5 | (6.4) | 175.0 | 65.3 | <.001 | 92.0 | (5.2) | 107.9 | (6.5) | 153.1 | 52.4 | <.001 |
| BMI (wt in kg/ht in m**2) | 28.2 | (5.2) | 31.2 | (6.2) | 32.7 | (6.2) | <.001 | 27.9 | (4.2) | 29.3 | (4.1) | 31.7 | (5.8) | <.001 |
| SBP (mmHG) | 115.0 | (14.9) | 114.6 | (15.8) | 121.7 | (15. | .002 | 114.7 | (14. | 114.0 | (13.9) | 118.6 | (14.9) | .004 |
| DBP (mmHG) | 69.6 | (8.9) | 68.8 | (10.4) | 69.9 | (7.7) | .718 | 71.1 | (9.5) | 71.6 | (9.0) | 71.9 | (9.0) | .642 |
| Number of types of HTN meds used past 30 days | 1.4 | (1.0) | 1.5 | (0.9) | 1.8 | (0.9) | .005 | 1.3 | (0.8) | 1.6 | (0.9) | 1.7 | (1.0) | <.001 |
| % | % | % | p | % | % | % | p | |||||||
| Hypertension>140/90 or reported tx | 54.8 | 45.7 | 69.3 | .007 | 38.8 | 44.0 | 56.7 | .001 | ||||||
| High blood cholesterol>=200 or brought meds | 86.4 | 85.3 | 91.7 | .392 | 80.2 | 80.7 | 82.7 | .819 | ||||||
| CHD in mother, father, sister, brother | 35.8 | 41.4 | 37.0 | .716 | 37.0 | 37.8 | 31.5 | .444 | ||||||
| Diabetes in mother, father, sister, brother | 30.4 | 60.3 | 56.8 | <.001 | 28.6 | 34.7 | 58.9 | <.001 | ||||||
| Lipid lowering drugs use past 30 days | 64.8 | 59.0 | 57.3 | .434 | 65.9 | 57.8 | 64.1 | .075 | ||||||
| Statin use past 30 days | 61.9 | 59.0 | 52.8 | .360 | 63.5 | 53.5 | 58.0 | .024 | ||||||
| HTN medication use past 30 days | 80.8 | 85.5 | 92.0 | .061 | 85.1 | 92.1 | 92.4 | .005 | ||||||
| Diuretic use past 30 days | 20.5 | 16.8 | 31.4 | .052 | 8.0 | 12.3 | 16.6 | .013 | ||||||
| Alpha blocker use past 30 days | 0.6 | 0.0 | 0.0 | .995 | 2.3 | 4.4 | 3.9 | .149 | ||||||
| Beta blocker use past 30 days | 63.7 | 67.4 | 73.0 | .316 | 73.1 | 79.8 | 72.9 | .091 | ||||||
| Calcium channel blocker use past 30 days | 22.1 | 20.5 | 33.8 | .072 | 13.5 | 23.6 | 29.6 | <.001 | ||||||
| Ace inhibitor use past 30 days | 27.9 | 37.3 | 32.5 | .301 | 31.1 | 32.5 | 38.1 | .295 | ||||||
| Angiotensin receptor blockers use past 30 days | 4.5 | 7.2 | 6.8 | .613 | 1.7 | 1.6 | 6.6 | .007 | ||||||
| Other type HTN med use past 30 days | 1.1 | 1.2 | 3.4 | .382 | 0.2 | 1.3 | 1.4 | .237 | ||||||
| DM medication use past 30 days-insulin or OHG | 0.0 | 0.0 | 70.8 | 0.0 | 0.0 | 73.2 | ||||||||
| Daily aspirin past 30 days | 82.4 | 83.1 | 69.6 | .035 | 86.3 | 85.2 | 80.4 | .229 | ||||||
| Caucasian race | 84.2 | 87.9 | 80.8 | .446 | 92.8 | 93.4 | 89.6 | .314 | ||||||
| Current smoker | 21.3 | 25.6 | 20.6 | .649 | 15.3 | 12.7 | 14.0 | .627 | ||||||
| Ever drink alcohol | 85.7 | 84.4 | 87.5 | .839 | 95.4 | 95.2 | 95.2 | .984 | ||||||
| Had recurrent event | 17.5 | 30.2 | 39.4 | .001 | 19.1 | 19.2 | 22.4 | .668 | ||||||
Diabetes defined as fasting glucose >125 or physician diagnosed and taking DM medication. Impaired fasting glucose defined as fasting glucose 100–125 mg/dl.
Recurrent event includes CHD and stroke (ICD 410–414,427,430–438), PTCA or angioplasty.
Some variables have missing data. P - values from GLM or logistic regression.