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. 2010 Feb 3;30(7):1265–1274. doi: 10.1038/jcbfm.2010.6

Figure 3.

Figure 3

Immunohistochemistry of IKKα, pIKKα, and pIKKα/β 1 h after 30 mins of tFCI in mice. (A) Weak IKKα immunopositivity was observed in sham-operated mice. (B) Cerebral ischemia induced an increase in expression and nuclear accumulation of IKKα in endothelial cells of the infarcted brains. (C, E) Phosphorylation of IKKα and IKKα/β was detected at low levels in sham-operated mice. (D, F) After tFCI, pIKKα and pIKKα/β significantly increased in endothelial cells 1 h after 30 mins of tFCI. Scale bar=25 μm (panel B), scale bar=100 μm (panel F), and scale bar=25 μm (panel F, inset).