Table 2.
Age Specific Rates of Serious Gastroenteritis Events in the HIVNET 012 and HIVIGLOB/ NVP Trials
| HIVNET 012 | HIVIGLOB/NVP | ||||
|---|---|---|---|---|---|
| Age Interval (months) |
Person Time of Follow-up (child-months) |
Rate per 1000 child-mos (95% CI) |
Person Time of Follow-up (child-months) |
Rate per 1000 child-mos (95% CI) |
p-value |
| 0-1 | 570 | 0 (0 - 4.3) | 666 | 1.5 (0.1 - 7.0) | 1.00 |
| 1-2 | 539 | 1.9 (0.2 - 8.7) | 642 | 4.7 (1.3 - 12.5) | 0.76 |
| 2-3 | 512 | 3.9 (0.8 - 12.5) | 627 | 9.6 (4.0 - 19.7) | 0.44 |
| 3-4 | 504 | 0 (0 - 4.9) | 617 | 16.2 (8.3 - 28.8) | 0.005** |
| 4-5 | 499 | 0 (0 - 4.9) | 612 | 9.8 (4.1 - 20.2) | 0.056 |
| 5-6 | 499 | 2.0 (0.2 - 9.4) | 610 | 9.8 (4.1 - 20.3) | 0.21 |
| 6-7 | 493 | 2.0 (0.2 - 9.5) | 603 | 13.3 (6.3 - 25.0) | 0.08 |
| 7-8 | 488 | 10.3 (3.9 - 22.5) | 599 | 15.0 (7.4 - 27.4) | 0.68 |
| 8-9 | 487 | 4.1 (0.8 - 13.2) | 596 | 10.1 (4.2 - 20.8) | 0.44 |
| 9-10 | 482 | 20.8 (10.7 - 36.8) | 594 | 8.4 (3.2 - 18.5) | 0.15 |
| 10-11 | 479 | 8.4 (2.8 - 19.9) | 592 | 10.1 (4.2 - 20.9) | 1.00 |
| 11-12 | 477 | 0 (0 - 5.2) | 590 | 3.4 (0.7 - 10.9) | 0.61 |
| 12-13 | 469 | 0 (0 - 5.3) | 587 | 8.5 (3.2 - 18.7) | 0.11 |
| 13-14 | 463 | 0 (0 - 5.3) | 579 | 1.7 (0.2 - 8.1) | 1.00 |
| 14-15 | 461 | 2.2 (0.2 - 10.1) | 559 | 7.2 (2.4 - 17.0) | 0.51 |
| 15-16 | 461 | 2.2 (0.2 - 10.1) | 534 | 5.6 (1.6 - 15.0) | 0.74 |
| 16-17 | 461 | 0 (0 - 5.3) | 511 | 7.8 (2.6 - 18.6) | 0.15 |
| 17-18 | 460 | 2.2 (0.2 - 10.1) | 473 | 2.1 (0.2 - 9.9) | 1.00 |
| 18-19 | 451 | 0 (0 - 5.5) | 163 | 0 (0 - 15.1) | 1.00 |
**
Significant at p-value of 0.05