Table 4.
Summary of suggestive and significant QTL (bold) identified and allelic affects at peak LOD score position. Genome-wide corrected significant and suggestive LOD scores are 3.2 and 2.1 respectively. Significant QTL are bold.
| Chr | Location (Mb) | LOD | P-valueπ | Increasing Allele | |
|---|---|---|---|---|---|
| Total Distance | 3 | 23.4 | 2.4 | 0.49 | C58 |
| 6 | 47.4 | 3.4 | 0.04 | B6/C58* | |
| 8 | 61.9 | 4.1 | 0.00 | B6 | |
| 17 | 46.0 | 2.8 | 0.25 | C58 | |
| Ambulatory Episodes | 3 | 86.0 | 2.5 | 0.42 | C58 |
| 6 | 49.0 | 2.7 | 0.28 | B6/C58* | |
| 8 | 66.6 | 3.8 | 0.01 | B6 | |
| 17 | 46.0 | 2.8 | 0.24 | C58 | |
| Percent Time Resting | 6 | 49.0 | 2.8 | 0.25 | B6 |
| 7 | 60.9 | 2.6 | 0.34 | B6 | |
| 8 | 89.5 | 3.5 | 0.03 | C58 | |
| 11 | 71.6 | 2.5 | 0.39 | B6 | |
| Percent Time in Center | 1 | 160.1 | 3.3 | 0.05 | B6 |
| 5 | 5.8 | 2.5 | 0.42 | C58 | |
| 6 | 96.3 | 2.1 | 0.62 | B6&C58† | |
| 8 | 57.7 | 3.2 | 0.10 | C58 | |
| 13 | 76.6 | 3.6 | 0.03 | B6 | |
| Average Velocity | 1 | 160.1 | 2.6 | 0.32 | B6 |
| 8 | 77.7 | 3.3 | 0.04 | C58 | |
| Rearing | 2 | 135.2 | 3.2 | 0.10 | C58 |
| 7 | 33.3 | 2.8 | 0.25 | B6 | |
| 16 | 56.1 | 2.5 | 0.41 | B6 |
*
Heterozygotes display increased total distance and more ambulatory episodes than either homozygote
†
Both B6 and C58 homozygotes spend more time in center than heterozygotes
π
P-values are adjusted for genomewide significance