. Author manuscript; available in PMC: 2011 Aug 1.

Published in final edited form as: Obesity (Silver Spring). 2009 Dec 24;18(8):1625–1631. doi: 10.1038/oby.2009.461

Table 3.

Multivariate relative risks (RR) and 95% confidence intervals (CI) of epithelial ovarian cancer according to hip circumference or BMI, by menopausal status, pooling the NHS and NHSII.

	Premenopausal			Postmenopausal

	Cases	Person-years	Multivariate^a RR (95% CI)	Cases	Person-years	Multivariate^a RR (95% CI)
Hip, inches
<37	12	148475	1.0 (REF)	59	118167	1.0 (REF)
38-<38.5	12	124457	1.09 (0.48–2.49)	56	131380	0.78 (0.53–1.13)
38.5-<40.5	15	110243	1.52 (0.66–3.48)	51	145767	0.60 (0.40–0.91)
40.5-<43	18	72864	2.60 (1.07–6.36)	37	113162	0.51 (0.32–0.83)
≥ 43-≤65	12	90832	1.54 (0.45–5.23)	54	127344	0.66 (0.37–1.16)
P-trend^b			0.04			0.03
P-interaction	0.01
<40.5	39	383175	1.0 (REF)	166	395314	1.0 (REF)
≥40.5	30	163696	1.86 (0.95–3.63)	91	240506	0.81 (0.58–1.14)
P-interaction	0.06
BMI, kg/m²
<21.0	44	459209	1.0 (REF)	79	216024	1.0 (REF)
21.0-<23	45	485819	0.84 (0.55–1.28)	108	287208	1.03 (0.77–1.38)
23-<25	43	398029	0.94 (0.61–1.43)	120	317031	1.05 (0.78–1.39)
25-<30	66	499993	1.03 (0.70–1.53)	168	509654	0.90 (0.69–1.18)
≥30	52	338193	1.15 (0.76–1.75)	115	302032	1.10 (0.82–1.48)
P-trend^b			0.22			0.75
P-interaction	0.22
<25	132	1343056	1.0 (REF)	307	820263	1.0 (REF)
≥25	118	838186	1.18 (0.91–1.52)	283	811685	0.94 (0.80–1.11)
P-interaction	0.08

Multivariate analyses adjusted for age at menarche, parity, duration of oral contraceptive use, tubal ligation history, height, family history of breast or ovarian cancer, caffeine intake, hysterectomy, and waist and BMI in the hip analysis. Postmenopausal analysis also adjusted for postmenopausal hormone use (never, past, current use).

P-value from multivariate model with hip or BMI using the quintile median as a continuous variable.