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. Author manuscript; available in PMC: 2010 Jun 21.
Published in final edited form as: Cancer Biol Ther. 2007 Aug 5;6(8):1165–1170. doi: 10.4161/cbt.6.8.4544

Table 1.

Relationship between p53 status and radiosensitivity of human prostate cancer cells.

Line p53 Allele p53 Status Radiosensitivity (Sf2)
Abbreviations: Wt = wild-type, ND = Not determined, SF2 = Surviving fraction after a 2 Gy dose of irradiation.
LNCaP Wt/Wt69 Wt 32.6
22Rv1 Q331R/Wt70 Partial function 30.7
DU145 P223L/V274F69 Dominant negative 80.2
PC-3 Deleted Null 52.2
Patient Q R282Q Gain of function33 ND