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. 2010 May 3;107(20):9281–9286. doi: 10.1073/pnas.1000473107

Fig. 2.

Fig. 2.

Germ-line genes are aberrantly expressed in Dnmt3b mutant embryos. (A) Germ-line gene expression changes in thymus derived from 18.5 dpc mEx3/mEx24 embryos. GenBank ID, symbol name (alias), chromosomal locus (Chr), fold-change expression, and corresponding P value (n = 5) are indicated. (B) RT-PCR analysis for detection of expression of the indicated germ-line gene expression (Maelstrom, Slc25a31, Syce1, Ddx4, Tex11) from mEx3/mEx24 (3/24) and WT MEF (12.5 dpc) or thymus, brain, liver, heart, lung, spleen, and kidney (18.5 dpc), and from untreated WT MEF or treated with AZA at 5 μM for 4 d. Mouse GAPDH transcripts were used as a normalization control.