Skip to main content
. 2010 May 3;107(20):9418–9423. doi: 10.1073/pnas.0913384107

Fig. 4.

Fig. 4.

Polyribosomes in spines. (A) EM of polyribosomes (arrows) in the dendritic shaft (Left) and spine (Right). (B) Reconstruction of a dendrite with polyribosomes (black) and postsynaptic densities (PSDs) (red). (C) There are more polyribosomes in both the dendritic shaft and spines with fear conditioning (FC). (D) Polyribosome frequency increases with FC in SA spine heads and smooth endoplasmic reticulum (sER)-free spine bases and necks relative to the naïve group. (E) sER-free spines with polyribosomes (+) have smaller PSDs than sER-free spines without polyribosomes (−) in all three training groups. (F) SA spines with polyribosomes have larger PSDs than SA spines without polyribosomes in the FC and naïve groups only. SA spines with polyribosomes in the naïve group (+, white bar) have larger PSDs than SA spines with polyribosomes in the conditioned inhibition group (+, gray bar, #P < 0.002). (G) PSD area on sER spines is unaffected by polyribosomes. All graphs show means ± SEM (*P < 0.04).