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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Med Mycol. 2010 Mar;48(2):263–272. doi: 10.1080/13693780903081976

FIG 2. Activity of CAP37 peptides against various Candida species.

FIG 2

The antifungal activity of CAP37 peptides, CAP3720-44 (20-44), CAP3720-44Ser26 (Ser 26), CAP3720-44Ser42 (Ser 42), and CAP3720-44Ser26/42 (Ser 26/42) was evaluated using a panel of Candida species that included C. guilliermondii, C. parapsilosis, C. pseudotropicalis, C. tropicalis, a blood isolate of C. albicans, two isolates of C. dubliniensis, three isolates of C. glabrata, one isolate of C krusei and two isolates of S. cerevisiae. Data reported here are for a single concentration of the four different peptides. The peptide concentration for C. guilliermondii and C. parapsilosis was 100 μg/ml (37.5 μM) whereas data for all other isolates were obtained using peptide concentrations of 400 μg/ml (150 μM). Values are expressed as ± standard error of the mean from three to four independent experiments performed in triplicate. Statistical analysis of data was performed using ANOVA followed by Tukey’s Multiple Comparison Test., ***P<0.001 represent significance values between control peptide and other peptides for an individual isolate. ##P<0.01 and ###P<0.001 represent significance values between CAP3720-44 and peptides CAP3720-44ser26 and CAP3720-44ser42 for an individual isolate.