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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Med Mycol. 2010 Mar;48(2):263–272. doi: 10.1080/13693780903081976

FIG 6. Time kill studies to determine fungicidal activity of CAP37 peptides.

FIG 6

C. albicans (3152A) (a), C. pseudotropicalis (b), C. glabrata (c, isolate iii in Figure 2), and S. cerevisiae (d, isolate ii in Figure 2) were selected for the kinetic studies. The fungal isolates were incubated with active peptide CAP3720-44 (20-44) at concentrations of 400, 200 and 100 μg/ml, and CAP3720-44ser26/42 (Ser26/42) at 400 and 200 μg/ml for 2, 5, 15, 30, 60, and 240 min. CFU were counted and the antifungal activity determined as described in the methods and materials section. Values are expressed as ± standard error of the mean from three or five independent experiments performed in triplicate. *P<0.05, **P<0.01 and ***P<0.001 compared to activity with CAP3720-44ser26/42 using ANOVA followed by Bonferroni’s Multiple Comparison Test.