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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: J Psychopharmacol. 2009 May 21;24(8):1165–1174. doi: 10.1177/0269881109105786

Table 2.

Table 2a: Anatomical Locations of the Planned Comparisons during Happiness Paradigm
MNI coordinates
Region Side X Y Z K T z p
Happy pictures
Clomipramine < Washout
 vmPFC (BA11) R 28 42 −8 26 3.38 2.74 0.003
 Insula R 40 14 8 77 3.43 2.77 0.003
R 32 −26 10 67 2.76 2.35 0.009
 Anterior Cingulate (BA24) R 4 28 22 29 3.05 2.54 0.005
 Anterior Cingulate (BA32) L −8 42 14 80 3.85 3 0.001
 Caudate body L −16 −14 26 157 4.11 3.13 0.001
R 16 −14 24 132 5.5 3.74 <0.001
 medial PFC (BA10) L −16 42 14 32 3.19 2.63 0.004
 Putamen L −14 2 10 66 2.34 2.07 0.019
Table 2b: Anatomical Locations of the Planned Comparisons during Fear Paradigm
MNI coordinates
Region Side X Y Z K T z p
Fear pictures
Clomipramine < Washout
 vLPFC (BA47) L −32 16 −2 24 3.22 2.61 0.005
 DLPFC (BA46) L −46 36 16 30 3.25 2.62 0.004
 Amygdala L −28 −8 −12 12 2.83 2.37 0.009
 Insula L −44 −16 18 97 5.06 3.49 <0.001
R 38 0 14 186 6.46 3.97 <0.001
 Parahippocampal Gyrus R 20 −34 −14 184 6.2 3.89 <0.001
 DLPFC (BA9) R 42 22 36 47 2.69 2.28 0.011
L −52 2 36 24 3.62 2.83 0.002
 Thalamus R 20 −14 6 253 4.31 3.17 <0.001
 Putamen R 28 −16 −4 114 4.65 3.32 <0.001
Neutral pictures
Clomipramine > Washout
 vmPFC (BA11) L −24 44 −6 8 2.22 1.96 0.025
Clomipramine < Washout
 Anterior Cingulate (BA24) L −4 22 22 24 2.55 2.19 0.014
 Amygdala R 28 −8 −14 65 3.58 2.81 0.002
Table 2c: Anatomical Locations of the Planned Comparisons during Anger Paradigm
MNI coordinates
Region Side X Y Z K T z p
Anger pictures
Clomipramine < Washout
 vLPFC (BA47) R 36 30 −2 22 3.49 2.8 0.003
R 26 16 −12 42 3.29 2.7 0.004
R 44 18 2 47 3.03 2.5 0.006
L −32 16 −12 72 8.49 4.6 <0.001
 DLPFC (BA46) R 42 36 16 53 4.15 3.2 0.001
 Amygdala R 28 −4 −16 61 3.02 2.5 0.006
 Insula L −32 16 −10 529 6.62 4.1 <0.001
L −50 −38 20 66 2.73 2.3 0.01
R 38 12 −10 82 4.78 3.4 <0.001
R 32 14 12 524 4.34 3.3 <0.001
R 42 −40 18 86 3.82 3 0.001
 Anterior Cingulate (BA24) R 4 30 24 35 3.61 2.9 0.002
L −2 32 18 41 2.82 2.4 0.008
 Anterior Cingulate (BA32) R 6 32 26 35 4.37 3.3 0.001
L −2 32 22 35 2.44 2.1 0.016
 Parahippocampal Gyrus R 16 −48 2 143 3.09 2.6 0.005
L −20 −34 −8 270 3 2.5 0.006
 Hippocampus L −26 −36 −4 9 2.73 2.3 0.01
 DLPFC (BA9) R 4 46 28 37 3.45 2. 8 0.003
R 34 20 34 129 3.31 2.7 0.003
 Thalamus R 8 −22 −2 621 5.02 3.5 <0.001
L −18 −22 0 282 6.72 4.1 <0.001
 Caudate body R 8 12 8 173 6.02 3.9 <0.001
 Caudate head R 8 18 6 169 6.31 4.0 <0.001
L −8 6 0 64 2.65 2.3 0.011
 Putamen R 22 −2 0 552 5.4 3.7 <0.001
L −18 4 −8 256 4.33 3.2 0.001
Neutral pictures
Clomipramine < Washout
 Insula L −40 −12 6 122 4.72 3.4 <0.001
R 40 −20 6 72 4.56 3.3 <0.001

vmPFC: ventromedial prefrontal cortex; R, right; L, left; BA, Brodmann area; Coordinates correspond to the stereotaxic array of Montreal Neurologic Institute; K: cluster size; PFC, prefrontal cortex

vLPFC: ventrolateral prefrontal cortex DLPFC: dorsolateral prefrontal cortex; R, right; L, left; BA, Brodmann area; Coordinates correspond to the stereotaxic array of Montreal Neurologic Institute; K: cluster size; vmPFC, ventromedial prefrontal cortex

vLPFC: ventrolateral prefrontal cortex DLPFC: dorsolateral prefrontal cortex; Coordinates correspond to the stereotaxic array of Montreal Neurologic Institute; BA, Brodmann area; R, right; L, left; K: cluster size