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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Pharmacol Biochem Behav. 2010 Apr 10;95(4):473–478. doi: 10.1016/j.pbb.2010.04.001

Figure 1. Time course of PRA effects on %PPI (A) and startle magnitude (B).

Figure 1

A: PRA 1.0 mg/kg significantly reduced PPI during the first 30 minutes of testing, with maximal effects during the third 10-minute block. (*, p<0.03) B: Startle-reducing effects of PRA persist across 60 min. This difference was significant during blocks 1,2,3, and 6. A decrease in startle magnitude during blocks 4 and 5 of the vehicle condition likely account for the lack of significance of PRA effects during these time periods.