Table 4.
(A) Univariate analysis of variables predicting outcome following retransplantation. (B) Multivariate analysis of the variables predicting outcome following retransplantation. (C) Stepwise logistic regression analysis of variables predicting outcome following retransplantation
| Variable | Odds ratio | 95% CI | P-value |
|---|---|---|---|
| (A) | |||
| Period of retransplantation | |||
| 1982–1988 | – | – | – |
| 1989–1994 | 3.24 | 1.59–6.58 | 0.001 |
| 1995–2001 | 1.96 | 1.04–3.69 | 0.036 |
| 2002–2007 | 1.68 | 0.89–3.18 | 0.108 |
| Early vs. late retransplantation | |||
| 0–7 days | – | – | – |
| 8–30 days | 1.93 | 1.19–3.14 | 0.008 |
| >30 days | 1.00 | 0.59–1.69 | 0.998 |
| Indications for retransplantation | |||
| Acute rejection | – | – | – |
| Hepatic artery thrombosis | 1.41 | 0.31–6.31 | 0.653 |
| Primary non-function | 0.73 | 0.26–2.12 | 0.570 |
| Graft infarction | 1.53 | 0.49–4.70 | 0.459 |
| Recurrent disease | 1.84 | 0.62–5.45 | 0.271 |
| Chronic rejection | 1.09 | 0.36–3.30 | 0.885 |
| Biliary complications | 0.71 | 0.24–2.09 | 0.538 |
| Others | 0.72 | 0.16–3.24 | 0.672 |
| Primary diagnosis | |||
| Alcoholic cirrhosis | – | – | – |
| Autoimmune hepatitis | 1.56 | 0.66–3.69 | 0.309 |
| Acute liver failure | 1.39 | 0.65–2.97 | 0.397 |
| Hepatitis C cirrhosis | 0.67 | 0.31–1.43 | 0.300 |
| Primary biliary cirrhosis | 1.24 | 0.54–2.84 | 0.606 |
| Primary sclerosing cholangitis | 1.05 | 0.57–1.96 | 0.868 |
| Others | 1.02 | 0.49–2.09 | 0.951 |
| Preoperative MELD score | |||
| ≤23 | – | – | – |
| >23 | 0.98 | 0.63–1.51 | 0.921 |
| Cold ischaemia time | |||
| >12 hours | – | – | – |
| ≤12 hours | 0.84 | 0.55–1.28 | 0.419 |
| Donor age | |||
| >55 years | – | – | – |
| ≤55 years | 0.72 | 0.31–1.66 | 0.445 |
| (B) | |||
| Period of retransplantation | |||
| 1982–1988 | – | – | – |
| 1989–1994 | 5.93 | 2.47–14.19 | 0.000 |
| 1995–2001 | 3.21 | 1.52–6.80 | 0.002 |
| 2002–2007 | 2.43 | 1.21–4.87 | 0.012 |
| Early vs. late retransplantation | |||
| 0–7 days | – | – | – |
| 8–30 days | 0.92 | 0.35–2.41 | 0.881 |
| >30 days | 0.50 | 0.23–1.07 | 0.075 |
| Indications for retransplantation | |||
| Acute rejection | – | – | – |
| Hepatic artery thrombosis | 1.50 | 0.26–8.65 | 0.645 |
| Primary non-function | 0.57 | 0.18–1.81 | 0.343 |
| Graft infarction | 0.94 | 0.20–4.32 | 0.937 |
| Recurrent disease | 1.52 | 0.41–5.63 | 0.530 |
| Chronic rejection | 0.85 | 0.26–2.75 | 0.787 |
| Biliary complications | 0.33 | 0.10–1.08 | 0.068 |
| Others | 0.28 | 0.05–1.44 | 0.130 |
| Primary diagnosis | |||
| Alcoholic cirrhosis | – | – | – |
| Autoimmune hepatitis | 1.72 | 0.69–4.30 | 0.239 |
| Acute liver failure | 1.40 | 0.59–3.29 | 0.440 |
| Hepatitis C cirrhosis | 0.45 | 0.20–1.04 | 0.063 |
| Primary biliary cirrhosis | 1.26 | 0.51–3.10 | 0.606 |
| Primary sclerosing cholangitis | 0.81 | 0.42–1.59 | 0.557 |
| Others | 0.84 | 0.39–1.82 | 0.670 |
| Preoperative MELD score | |||
| ≤23 | – | – | – |
| >23 | 0.93 | 0.54–1.62 | 0.821 |
| Cold ischaemia time | |||
| >12 hours | – | – | – |
| ≤12 hours | 0.61 | 0.38–0.98 | 0.042 |
| Donor age | |||
| >55 years | – | – | – |
| ≤55 years | 1.13 | 0.47–2.74 | 0.775 |
| (C) | |||
| Preoperative MELD score ≤23 | 1.03 | 1.00–1.06 | 0.029 |
| Donor age ≤55 years | 1.02 | 1.00–1.04 | 0.036 |
95% CI, 95% confidence interval; MELD, Model for End-stage Liver Disease