Table 1.
Serologic markers of HBV infection in two patients with HBV-associated ALF
Marker | On admission | Day 3 | Day 4 |
Patient 1 | |||
HBsAg | Positive | Positive | Positive |
Concentration (μg/mL) | 1.74 | ||
Anti-HBs (mIU/mL) | 0 | 0 | 0 |
Anti-HBc | Positive | Positive | Positive |
Titer | 1:128 | ||
IgM anti-HBc | Positive | Positive | Positive |
Titer | 1:524,288 | ||
HBeAg | Negative | Negative | Negative |
Anti-HBe | Borderline positive | Positive | Positive |
HBV DNA (copies/mL) | 218,000 | ||
Patient 2 | |||
HBsAg | Borderline positive | Negative | Negative |
Concentration (μg/mL) | 0 | ||
Anti-HBs (mIU/mL) | 5.9 | 8.0 | |
Anti-HBc | Positive | Positive | Positive |
Titer | 1:256 | ||
IgM anti-HBc | Positive | Positive | Positive |
Titer | 1:524,288 | ||
HBeAg | Negative | Negative | Negative |
Anti-HBe | Positive | Positive | Positive |
HBV DNA (copies/mL) | 185,000 | 7,500 |