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. 2010 Apr 26;107(19):8824–8829. doi: 10.1073/pnas.1001702107

Fig. 2.

Fig. 2.

The H3K4me3 epigenome of PFC neurons is different from nonneuronal cells. Heatmaps showing Pearson correlation coefficients for pair-wise comparison of raw tag counts within 2 kb of annotated TSS. (Lower) 11 neuronal (NeuN+) samples from subjects 1–11 (female pink, male blue), two nonneuronal (NeuN−) samples from subjects 6 and 11, and CD4+ T cells and two lymphocyte-derived cell lines K562 and GM12878. (Upper) The same comparison for the 11 neuronal samples as in Bottom, but with a different color scale to highlight differences between neuronal samples. Notice (Lower) very high levels of correlation between NeuN+ samples, but not between NeuN+ and NeuN− samples or lymphocytes. Notice further (Upper) that correlations are higher for neuronal samples closer in age.