Table 1.
Genotype and allele frequencies of DEFB1 rs1800972 and rs11362 in CD
| SNP | Crohn´s disease, n (%) | Ileal (L1), n (%) | Colonic (L2), n (%) | Ileocolonic (L3), n (%) | ||
| rs1800972 | L1 vs. L2 | L1 vs. L2 + L3 | ||||
| CC | 170 (68.27) | 40 (58.82) | 53 (72.60) | 77 (71.30) | ||
| CG | 70 (28.11) | 23 (33.82) | 19 (26.03) | 28 (25.93) | ||
| GG | 9 (3.61) | 5 (7.35) | 1 (1.37) | 3 (2.78) | ||
| C | 410 (82.33) | 103 (75.74) | 125 (85.62) | 182 (84.26) | C vs. G | C vs. G |
| G | 88 (17.67) | 33 (24.26) | 21 (14.38) | 34 (15.74) | P = 0.035; OR = 0.524 | P = 0.018; OR = 0.559 |
| rs11362 | ||||||
| GG | 82 (33.06) | 27 (40.30) | 24 (32.88) | 31 (28.70) | ||
| GA | 113 (45.56) | 29 (43.28) | 34 (46.58) | 50 (46.30) | ||
| AA | 53 (21.37) | 11 (16.42) | 15 (20.55) | 27 (25.00) | ||
| G | 277 (55.85) | 83 (61.94) | 82 (56.16) | 112 (51.85) | G vs. A | G vs. A |
| A | 219 (44.15) | 51 (38.06) | 64 (43.84) | 104 (48.15) | P = 0.326; OR = 1.270 | P = 0.096; OR = 1.409 |