Schematic diagram illustrating therapeutic approaches based on the degree of diastolic dysfunction. LV: left ventricle, LVH: left ventricular Hypertrophy, DM: diabetes mellitus, CAD: coronary artery disease, DOE: dyspnea on exertion, ACE: angiotensin converting enzyme, ARB: angiotensin receptor blocker, NYHA: New York Heart Association, HF: heart failure.